Technology of Prepare Nitroso-malonic ester and Disposal of the Three wastes 亚硝基丙二酸酯的制备及三废治理
When the amount of catalyst is 0.03 mol ( based on F-) and the molar ratio of acrylon to malonic ester is 1:3, the yield of Michael addition reaction was over 88% after 3 hours. 当催化剂用量以F-计为0.03mol,反应原料丙二酸二乙酯与丙稀腈之比为3:1,反应时间为2h,加成反应的转化率最高。
In the recent report about the one pot synthesis of malonic acid ester needs tert-butyl hydroperoxide exist some defect such as expensive, explosive, so it was not suit for the industrialization production. 在最近报道的丙二酸酯类化合物一步法合成的方法中使用的氧化剂叔丁基过氧化氢存在价格高、易爆炸等缺点,不适合工业化生产。
This method provided a new way which was simply operated, excellent yields and environmental to get many nitro compound introductions. Third, the malonic acid ester compounds are the important intermediates in dye and spice and also have important use in fields of medicine. 本课题为硝基官能团的引入提供了一条操作简便、绿色环保、收率良好的新方法。第三,丙二酸酯类化合物是染料和香料的重要中间体,并用作合成医药的原料。